Immunization Elicits Antigen-Specific Antibody Sequestration in Dorsal Root Ganglia Sensory Neurons
نویسندگان
چکیده
منابع مشابه
caspase-mediated apoptosis in sensory neurons of cultured dorsal root ganglia in adult mouse
objective: sensory neurons in dorsal root ganglia (drg) undergo apoptosis after peripheral nerve injury. the aim of this study was to investigate sensory neuron death and the mechanism involved in the death of these neurons in cultured drg. materials and methods: in this experimental study, l5 drg from adult mouse were dissected and incubated in culture medium for 24, 48, 72 and 96 hours. fresh...
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Paclitaxel is an antineoplastic drug, and its usage is often limited by severe peripheral polyneuropathy characterized by symptoms in remote extremities. It is suggested that subpopulations of dorsal root ganglion (DRG) neurons are impacted functionally and/or structurally. In this study, the neurotoxic effect of this drug in cultured rat DRG neurons was analyzed by measuring their neurite leng...
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Background and Objective: Sensory neurons have critical role in improvement of functional outcome of any neuroprotective strategy. The herbal medicine Nepeta menthoides has been reported to have anti-apoptotic effect on axotomized spinal motoneurons. In the present study, the putative neuroprotective effect of Nepeta menthoides on the axotomized dorsal root ganglion sensory neurons in neonate r...
متن کاملRole of a voltage-sensitive calcium channel blocker on inhibition of apoptosis in sensory neurons of cultured dorsal root ganglia in adult rat
Introduction: Under pathological conditions, abnormal increase in intracellular calcium concentrations is believed to induce cell death. In the present study, a voltage-sensitive calcium channel blocker (loperamide hydrochloride) was used to investigate its role in inhibition of apoptosis in sensory neurons of cultured spinal dorsal root ganglia (DRG). Methods: L5 DRG from adult rats were di...
متن کاملCaspase-Mediated Apoptosis in Sensory Neurons of Cultured Dorsal Root Ganglia in Adult Mouse
OBJECTIVE Sensory neurons in dorsal root ganglia (DRG) undergo apoptosis after peripheral nerve injury. The aim of this study was to investigate sensory neuron death and the mechanism involved in the death of these neurons in cultured DRG. MATERIALS AND METHODS In this experimental study, L5 DRG from adult mouse were dissected and incubated in culture medium for 24, 48, 72 and 96 hours. Fresh...
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ژورنال
عنوان ژورنال: Frontiers in Immunology
سال: 2018
ISSN: 1664-3224
DOI: 10.3389/fimmu.2018.00638